Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 20/20 | 0.69 |
| ▸ | PPARD | Q03181 | 20/20 | 0.69 |
| ▸ | PPARA | Q07869 | 17/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6054878 | 0.93 | PPARG (0.80) | PPARGPPARDPPARA | |
| SCHEMBL6054856 | 0.88 | PPARG (0.70) | PPARGPPARDPPARA | |
| SCHEMBL5988765 | 0.87 | PPARG (0.64) | PPARGPPARDPPARA | |
| SCHEMBL5988760 | 0.87 | PPARG (0.64) | PPARGPPARDPPARA | |
| SCHEMBL5989104 | 0.86 | PPARG (0.85) | PPARGPPARDPPARA | |
| SCHEMBL5989109 | 0.86 | PPARG (0.85) | PPARGPPARDPPARA | |
| SCHEMBL5989743 | 0.86 | PPARG (0.85) | PPARGPPARDPPARA | |
| SCHEMBL5991697 | 0.85 | PPARG (0.86) | PPARGPPARDPPARA | |
| SCHEMBL6054833 | 0.83 | PPARG (0.63) | PPARGPPARDPPARA | |
| SCHEMBL5990190 | 0.83 | PPARG (0.63) | PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660428-A1 | PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005019151-A1 | PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-03-03 | — | — | WO | disclosed |