Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 19/20 | 1.00 |
| ▸ | ABL1 | P00519 | 12/20 | 1.00 |
| ▸ | EGFR | P00533 | 6/20 | 1.00 |
| ▸ | KDR | P35968 | 6/20 | 1.00 |
| ▸ | PIK3CD | O00329 | 5/20 | 1.00 |
| ▸ | PIK3CA | P42336 | 5/20 | 1.00 |
| ▸ | PIK3CB | P42338 | 5/20 | 1.00 |
| ▸ | MTOR | P42345 | 5/20 | 1.00 |
| ▸ | PIK3CG | P48736 | 5/20 | 1.00 |
| ▸ | PRKDC | P78527 | 5/20 | 1.00 |
| ▸ | HCK | P08631 | 5/20 | 1.00 |
| ▸ | EPHB4 | P54760 | 4/20 | 1.00 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | LCK | P06239 | 2/20 | 0.66 |
| ▸ | FYN | P06241 | 2/20 | 0.66 |
| ▸ | YES1 | P07947 | 2/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14617287 | 0.91 | SRC (1.00) | SRCABL1EGFRKDRPIK3CD | |
| SCHEMBL14617301 | 0.85 | SRC (0.89) | SRCABL1EGFRKDRPIK3CD | |
| SCHEMBL234181 | 0.84 | SRC (0.80) | SRCABL1EGFRKDRPIK3CD | |
| SCHEMBL13019681 | 0.84 | SRC (0.80) | SRCABL1EGFRKDRPIK3CD | |
| SCHEMBL14617291 | 0.84 | SRC (1.00) | SRCABL1EGFRKDRPIK3CD | |
| SCHEMBL2469676 | 0.81 | SRC (1.00) | SRCABL1EGFRKDRPIK3CD | |
| SCHEMBL409444 | 0.81 | SRC (0.82) | SRCABL1EGFRKDRPIK3CD | |
| SCHEMBL13019808 | 0.81 | SMN1; SMN2 (0.75) | SRCABL1EGFRKDRPIK3CD | |
| SCHEMBL13019692 | 0.81 | SRC (0.75) | SRCABL1EGFRKDRPIK3CD | |
| SCHEMBL407934 | 0.80 | SRC (1.00) | SRCABL1EGFRKDRPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040197335-A1 | Non-myeloablative tolerogenic treatment with tyrphostins | HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENT LTD. (IL) | 2004-10-07 | — | — | US | claimed |
| WO-2003065971-A9 | NON-MYELOABLATIVE TOLEROGENIC TREATMENT WITH TYRPHOSTINS | YISSUM RES DEV CO (IL) | 2003-11-20 | — | — | WO | claimed |
| EP-1482983-A4 | NON-MYELOABLATIVE TOLEROGENIC TREATMENT WITH TYRPHOSTINS | YISSUM RES DEV CO (IL) | 2006-07-12 | — | — | EP | disclosed |
| EP-1482983-A2 | NON-MYELOABLATIVE TOLEROGENIC TREATMENT WITH TYRPHOSTINS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2004-12-08 | — | — | EP | disclosed |
| US-20040197335-A1 | Non-myeloablative tolerogenic treatment with tyrphostins | HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENT LTD. (IL) | 2004-10-07 | — | — | US | disclosed |
| WO-2003065971-A2 | NON-MYELOABLATIVE TOLEROGENIC TREATMENT WITH TYRPHOSTINS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2003-08-14 | — | — | WO | disclosed |