Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8004969 | 0.82 | — | — | |
| SCHEMBL17799145 | 0.75 | KMT2A (0.43) | KMT2AALDH1A1CA1CA2CA4 | |
| SCHEMBL30982279 | 0.75 | KMT2A (0.43) | KMT2AALDH1A1CA1CA2CA4 | |
| SCHEMBL354994 | 0.75 | KMT2A (0.43) | KMT2AALDH1A1CA1CA2CA4 | |
| SCHEMBL6244928 | 0.75 | KMT2A (0.43) | KMT2AALDH1A1CA1CA2CA4 | |
| SCHEMBL2194749 | 0.73 | KMT2A (0.42) | KMT2AALDH1A1CA1CA2CA4 | |
| SCHEMBL2196527 | 0.73 | KMT2A (0.42) | KMT2AALDH1A1CA1CA2CA4 | |
| SCHEMBL2194743 | 0.73 | KMT2A (0.42) | KMT2AALDH1A1CA1CA2CA4 | |
| SCHEMBL2193711 | 0.73 | KMT2A (0.42) | KMT2AALDH1A1CA1CA2CA4 | |
| SCHEMBL6055714 | 0.73 | KMT2A (0.42) | KMT2AALDH1A1CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1264594-B1 | Melanin production inhibitors and skincare products containing such inhibitors | TAKASAGO PERFUMERY CO LTD (JP) | 2006-11-29 | — | — | EP | disclosed |
| US-6759557-B2 | MACROCYCLIC HYDROCARBON RINGS WITH HYDROXYL AND/OR KETONE FUNCTIONALITIES, SUCH AS CYCLOTETRADECANONE OR 2-HYDROXYCYCLOHEXADECANONE, OPTIONALLY WITH SKIN WHITENING AGENTS AND/OR UV ABSORBERS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2004-07-06 | — | — | US | disclosed |
| EP-1264594-A2 | Melanin production inhibitors and skincare products containing such inhibitors | Takasago International Corporation (JP) | 2002-12-11 | — | — | EP | disclosed |