Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER2 | P43116 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | BRS3 | P32247 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13399034 | 0.89 | PTGER2 (0.49) | PTGER2KMT2AMEN1MAPTPKM | |
| SCHEMBL5049363 | 0.88 | PTGER2 (0.53) | PTGER2KMT2AMEN1MAPTPKM | |
| SCHEMBL5049397 | 0.88 | PTGER2 (0.49) | PTGER2KMT2AMEN1MAPTPKM | |
| SCHEMBL13399184 | 0.85 | PTGER2 (0.58) | PTGER2KMT2AMEN1MAPTPKM | |
| SCHEMBL13399232 | 0.83 | PTGER2 (0.62) | PTGER2PTGER4CA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL5043372 | 0.81 | PTGER2 (0.71) | PTGER2PTGER4CA12CA1CA2 | |
| SCHEMBL5043416 | 0.80 | PTGER2 (0.60) | PTGER2PTGER4CA12CA1CA2 | |
| SCHEMBL5046726 | 0.73 | PTGER2 (0.62) | PTGER2KMT2AMEN1PTGER4CA12 | |
| SCHEMBL5046588 | 0.72 | PTGER2 (0.54) | PTGER2PTGER4 | |
| SCHEMBL5047921 | 0.72 | PTGER2 (0.58) | PTGER2PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1021410-B1 | PROSTAGLANDIN AGONISTS AND THEIR USE TO TREAT BONE DISORDERS | PFIZER (US) | 2006-12-27 | — | — | EP | disclosed |