Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.53 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.53 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6058824 | 0.95 | TSHR (0.61) | TSHRALDH1A1LMNAMAPK1TP53 | |
| SCHEMBL9799473 | 0.83 | TSHR (0.73) | TSHRALDH1A1LMNAMAPK1TP53 | |
| SCHEMBL19348915 | 0.83 | TSHR (0.73) | TSHRALDH1A1LMNAMAPK1TP53 | |
| SCHEMBL828502 | 0.83 | TSHR (0.73) | TSHRALDH1A1LMNAMAPK1TP53 | |
| SCHEMBL20695622 | 0.83 | TSHR (0.73) | TSHRALDH1A1LMNAMAPK1TP53 | |
| SCHEMBL18106214 | 0.83 | TSHR (0.73) | TSHRALDH1A1LMNAMAPK1TP53 | |
| SCHEMBL18109769 | 0.83 | TSHR (0.73) | TSHRALDH1A1LMNAMAPK1TP53 | |
| SCHEMBL19348920 | 0.83 | TSHR (0.73) | TSHRALDH1A1LMNAMAPK1TP53 | |
| SCHEMBL829747 | 0.83 | TSHR (0.73) | TSHRALDH1A1LMNAMAPK1TP53 | |
| SCHEMBL20695609 | 0.83 | TSHR (0.73) | TSHRALDH1A1LMNAMAPK1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678218-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.r.l. (IT) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005047351-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2005-05-26 | — | — | WO | disclosed |