SCHEMBL6059424

SCHEMBL6059424

O=C(c1ccc(Cl)cc1)c1ccccc1Oc1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A1 P22736 1/20 0.60
L3MBTL1 Q9Y468 4/20 0.58
ALDH1A1 P00352 3/20 0.58
GAA P10253 1/20 0.58
HPGD P15428 1/20 0.58
HTT P42858 1/20 0.58
ATM Q13315 1/20 0.58
CTNNB1 P35222 1/20 0.56
MAPT P10636 2/20 0.54
SRD5A2 P31213 1/20 0.49
SMN1; SMN2 Q16637 2/20 0.48
LMNA P02545 1/20 0.48
MAPK8 P45983 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
CYP1A2 P05177 1/20 0.48
CYP3A4 P08684 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
KMT2A Q03164 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29575432 0.92 CTNNB1 (0.65) L3MBTL1ALDH1A1CTNNB1MAPTSRD5A2
SCHEMBL8746846 0.92 CTNNB1 (0.65) L3MBTL1ALDH1A1CTNNB1MAPTSRD5A2
SCHEMBL9481869 0.91 NR4A1 (0.54) NR4A1L3MBTL1ALDH1A1GAAHPGD
SCHEMBL10874570 0.89 NR4A1 (0.55) NR4A1L3MBTL1ALDH1A1GAAHPGD
SCHEMBL10448654 0.88 SRD5A2 (0.62) CTNNB1SRD5A2SMN1; SMN2KMT2AMEN1
SCHEMBL4631035 0.88 CTNNB1 (0.65) L3MBTL1ALDH1A1GAACTNNB1MAPT
Benzophenone SCHEMBL28468666 0.86 CTNNB1 (0.62) L3MBTL1ALDH1A1GAACTNNB1MAPT
SCHEMBL4339742 0.86 MAPT (0.50) NR4A1L3MBTL1ALDH1A1GAAHPGD
SCHEMBL11451250 0.86 MAPT (0.50) NR4A1L3MBTL1ALDH1A1GAAHPGD
SCHEMBL7976723 0.85 CTNNB1 (0.57) L3MBTL1CTNNB1SRD5A2SMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1138712-B1 Polyarylene copolymers and proton-conductive membrane JSR CORP (JP) 2006-01-18 EP disclosed
US-6933068-B2 Polymer electrolyte membrane and solid polymer electrolyte fuel cell using same HONDA GIKEN KOGYO KABUSHIKI KAISHA (JP) 2005-08-23 US disclosed
US-20020172850-A1 Polymer electrolyte membrane and solid polymer electrolyte fuel cell using same HONDA GIKEN KOGYO KABUSHIKI KAISHA, JSR CORPORATION 2002-11-21 US disclosed
EP-0307710-A1 Process for producing aromatic polyether ketones BAYER AG (DE) 1989-03-22 EP disclosed