⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4119428 | 0.71 | — | — | |
| SCHEMBL617841 | 0.69 | — | — | |
| SCHEMBL6095535 | 0.67 | — | — | |
| SCHEMBL5769036 | 0.67 | — | — | |
| SCHEMBL8983859 | 0.65 | — | — | |
| SCHEMBL14814425 | 0.65 | — | — | |
| SCHEMBL2161853 | 0.64 | — | — | |
| SCHEMBL9455088 | 0.62 | — | — | |
| SCHEMBL1467334 | 0.61 | — | — | |
| SCHEMBL2508494 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060004230-A1 | Process for the preparation of terbinafine and salts thereof | CHEMAGIS LTD. (IL) | 2006-01-05 | — | — | US | disclosed |
| US-5817875-A | Methods for the manufacture of terbinafine | KARIMIAN KHASHAYAR (CA) | 1998-10-06 | — | — | US | disclosed |
| EP-0710241-A1 | NOVEL SILYLATED BENZYLAMINE DERIVATIVES, SALTS THEREOF, METHODS OF MANUFACTURE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PIERRE FABRE MEDICAMENT (FR) | 1996-05-08 | — | — | EP | disclosed |
| US-5439932-A | Anticholesterol agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-08-08 | — | — | US | disclosed |
| WO-1995003313-A1 | NOVEL SILYLATED BENZYLAMINE DERIVATIVES, SALTS THEREOF, METHODS OF MANUFACTURE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PIERRE FABRE MEDICAMENT (FR) | 1995-02-02 | — | — | WO | disclosed |
| US-5306728-A | Substituted amine derivatives having antihyperlipemia activity | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-04-26 | — | — | US | disclosed |
| US-4751245-A | Antifungal derivatives of N-(6,6-dimethyl-2-hepten-4-ynyl)-1-naphthalenemethanamine and method of using same | E. R. SQUIBB & SONS, INC. (US) | 1988-06-14 | — | — | US | disclosed |
| EP-0251574-A2 | Antifungal derivatives of N-(6,6-dimethyl-2-hepten-4-ynyl)-1-naphthalenemethanamine and method of using same | E.R. Squibb & Sons, Inc. (US) | 1988-01-07 | — | — | EP | disclosed |