SCHEMBL60598

SCHEMBL60598

[C]#CC(C)(C)CC#CCC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9305600 0.74
SCHEMBL9845363 0.70
SCHEMBL3551592 0.67
SCHEMBL8388656 0.67
SCHEMBL11044825 0.65
SCHEMBL7109 0.65
SCHEMBL1894280 0.65
SCHEMBL1265508 0.63
SCHEMBL3552367 0.63
SCHEMBL1265688 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 777 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112689634-B SMAD3 inhibitors 莫扎制药有限公司 2024-07-16 CN disclosed
CN-118355029-A Methods of treating diffuse large B-cell lymphomas using anti-CD 79B immunoconjugates 基因泰克公司 2024-07-16 CN disclosed
CN-111558049-B Methylene carbamate linkers for use with target-drug conjugates 西雅图基因公司 2024-06-21 CN disclosed
CN-111569086-B Methylene carbamate linkers for use with target-drug conjugates 西雅图基因公司 2024-06-21 CN disclosed
EP-4385991-A1 COMPOUND HAVING SHP2 PROTEIN DEGRADING ACTIVITY, AND MEDICAL USES THEREOF Ubix Therapeutics, Inc. (KR) 2024-06-19 EP disclosed
CN-118201946-A Lipidated polymyxin analogues 奥克兰联合服务有限公司 2024-06-14 CN disclosed
EP-3280402-B1 TOLAN COMPOUNDS FOR PROMOTING WOUND HEALING BIOMENDICS LLC (US) 2024-06-05 EP disclosed
US-20240158439-A1 INHIBITORS OF ANTIGEN PRESENTATION BY MHC CLASS II HLA-DRB1*15:01 MOLECULES WITH ENHANCED METABOLIC STABILITY PROVID PHARMACEUTICALS INC. 2024-05-16 US disclosed
CN-117881655-A Ultraviolet radiation and visible radiation absorbing compounds 爱尔克米亚公司 2024-04-12 CN disclosed
CN-117881678-A Compound with SHP2 protein degradation activity and medical application thereof 尤比克斯治疗公司 2024-04-12 CN disclosed
US-20040028660-A1 Methods of using JNK or MKK inhibitors to modulate cell differentiation and to treat myeloproliferative disorders and myelodysplastic syndromes ANTHROGENESIS CORPORATION 2004-02-12 US disclosed
WO-2004009610-A2 USE OF NUCLEOSIDE COMPOUNDS FOR NONSENSE SUPPRESSION AND THE TREATMENT OF GENETIC DISEASES PTC THERAPEUTICS, INC. (US) 2004-01-29 WO disclosed
WO-2004009563-A1 5-ARYLTETRAZOLE COMPOUNDS, COMPOSITIONS THEREOF, AND USES THEREFOR INOTEK PHARMACEUTICALS CORPORATION (US) 2004-01-29 WO disclosed
WO-2004009609-A2 NUCLEOSIDE COMPOUNDS AND THEIR USE FOR TREATING CANCER AND DISEASES ASSOCIATED WITH SOMATIC MUTATIONS PTC THERAPEUTICS, INC. (US) 2004-01-29 WO disclosed
WO-2004009533-A1 ACETYLAMINO BENZOIC ACID COMPOUNDS AND THEIR USE FOR NONSENSE SUPPRESSION AND THE TREATMENT OF DISEASE PTC THERAPEUTICS, INC. (US) 2004-01-29 WO disclosed
US-20040019208-A1 5-Aryltetrazole Compounds, compositions thereof, and uses therefor INOTEK PHARMACEUTICALS CORPORATION 2004-01-29 US disclosed
WO-2004004774-A2 COMPOSITIONS COMPRISING PANTHETINE FOR THE TREATMENT OF DYSLIPIDEMIA ESPERION THERAPEUTICS, INC. (US) 2004-01-15 WO disclosed
WO-2004002983-A2 THERAPEUTIC PIPERAZINE DERIVATIVES USEFUL FOR TREATING PAIN EURO-CELTIQUE, S.A. (LU) 2004-01-08 WO disclosed
WO-2003105774-A2 COMPOUNDS USEFUL FOR THE TREATMENT OF CANCER, COMPOSITIONS THEREOF AND METHODS THEREWITH SIGNAL PHARMACEUTICALS, INC. (US) 2003-12-24 WO disclosed
WO-2003102151-A2 MODULATING CELL DIFFERENTIATION AND TREATING MYELOPROLIFERTIVE DISORDERS WITH JNK/MKK INHIBITORS CELGENE CORPORATION (US) 2003-12-11 WO disclosed