Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 11/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.63 |
| ▸ | TP53 | P04637 | 3/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | THRB | P10828 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL6060812 | 0.98 | TSHR (0.60) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| Methacrylic Acid SCHEMBL16197602 | 0.93 | TSHR (0.73) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL4945997 | 0.89 | TSHR (0.79) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL11439251 | 0.89 | TSHR (0.79) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL36437 | 0.89 | TSHR (0.79) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL8850371 | 0.89 | TSHR (0.79) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL10390293 | 0.89 | TSHR (0.79) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL5685352 | 0.89 | TSHR (0.79) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL8850772 | 0.89 | TSHR (0.79) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL246221 | 0.89 | TSHR (0.79) | TSHRALDH1A1TP53HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1656116-A2 | POLYMERIC SYSTEMS FOR CONTROLLED DRUG THERAPY | Vista Scientific LLC (US) | 2006-05-17 | — | — | EP | disclosed |
| WO-2005023181-A2 | POLYMERIC SYSTEMS FOR CONTROLLED DRUG THERAPY | VISTA SCIENTIFIC (US) | 2005-03-17 | — | — | WO | disclosed |