⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6060957 | 1.00 | — | — | |
| SCHEMBL8577452 | 0.81 | — | — | |
| SCHEMBL8577455 | 0.81 | — | — | |
| SCHEMBL8575836 | 0.74 | — | — | |
| SCHEMBL8575843 | 0.74 | — | — | |
| SCHEMBL8574657 | 0.72 | — | — | |
| SCHEMBL9233132 | 0.68 | — | — | |
| SCHEMBL2161868 | 0.64 | — | — | |
| SCHEMBL2161865 | 0.64 | — | — | |
| Bromide SCHEMBL28607029 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7091240-B2 | Tubulin binding ligands and corresponding prodrug constructs | OXIGENE, INC. (US) | 2006-08-15 | — | — | US | disclosed |
| US-20040044059-A1 | Destroying tumor cell vasculation; antitumor agents; anticancer agents | MATEON THERAPEUTICS, INC. | 2004-03-04 | — | — | US | disclosed |
| US-6593374-B2 | Such as 3-(3'4'5'-trimethoxybenzoyl)-2-(3'benzylphosphate 4'methoxyphenyl)-6-methoxybenzo(b)thiophene; functionalized to prepare phosphate esters, phosphate salts, and phosphoramidates useful as antitumor agents | BAYLOR UNIVERSITY | 2003-07-15 | — | — | US | disclosed |
| US-20020055643-A1 | Tubulin binding ligands and corresponding prodrug constructs | MATEON THERAPEUTICS, INC. | 2002-05-09 | — | — | US | disclosed |
| WO-1996003124-A9 | DYNEMICIN ANALOGS | — | 1996-03-14 | — | — | WO | disclosed |
| WO-1996003124-A1 | DYNEMICIN ANALOGS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1996-02-08 | — | — | WO | disclosed |