Iodide

Iodide

SCHEMBL6060987

[I-].[I-].c1ccc([P+](CCCCC[P+](c2ccccc2)(c2ccccc2)c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG

The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.70
CHRNA7 P36544 9/20 0.56
ALDH1A1 P00352 1/20 0.52
CYP1A2 P05177 1/20 0.52
CYP2D6 P10635 1/20 0.52
TSHR P16473 1/20 0.52
CYP2C19 P33261 1/20 0.52
TRAP1 Q12931 3/20 0.49
SNCA P37840 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodide SCHEMBL8999578 1.00 HIF1A (0.70) HIF1ACHRNA7ALDH1A1CYP1A2CYP2D6
Iodide SCHEMBL6060986 1.00 HIF1A (0.70) HIF1ACHRNA7ALDH1A1CYP1A2CYP2D6
SCHEMBL31447355 0.97 HIF1A (0.74) HIF1ACHRNA7ALDH1A1CYP1A2CYP2D6
Iodide SCHEMBL6060724 0.97 HIF1A (0.74) HIF1ACHRNA7ALDH1A1CYP1A2CYP2D6
SCHEMBL29438162 0.97 HIF1A (0.74) HIF1ACHRNA7ALDH1A1CYP1A2CYP2D6
SCHEMBL29466951 0.97 HIF1A (0.74) HIF1ACHRNA7ALDH1A1CYP1A2CYP2D6
Hydrochloric Acid SCHEMBL7628004 0.95 HIF1A (0.70) HIF1ACHRNA7ALDH1A1CYP1A2CYP2D6
Bromide SCHEMBL8761335 0.95 HIF1A (0.70) HIF1ACHRNA7ALDH1A1CYP1A2CYP2D6
Hydrochloric Acid SCHEMBL6061039 0.95 HIF1A (0.70) HIF1ACHRNA7ALDH1A1CYP1A2CYP2D6
Bromide SCHEMBL4184421 0.95 HIF1A (0.70) HIF1ACHRNA7ALDH1A1CYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150198913-A1 TRANSFER ASSIST MEMBERS XEROX CORPORATION (US) 2015-07-16 US disclosed
US-9069294-B1 Transfer assist members XEROX CORPORATION (US) 2015-06-30 US disclosed
US-20060229400-A1 Powder coating matting agent comprising ester amide condensation product FLETCHER TIM 2006-10-12 US disclosed
US-20050288450-A1 Coating matting agent comprising amide condensation product FLETCHER TIM 2005-12-29 US disclosed
EP-1509561-A1 POWDER COATING MATTING AGENT COMPRISING ESTER AMIDE CONDENSATION PRODUCT Grace GmbH & Co. KG (DE) 2005-03-02 EP disclosed
WO-2003102048-A1 POWDER COATING MATTING AGENT COMPRISING ESTER AMIDE CONDENSATION PRODUCT GRACE GMBH & CO. KG (DE) 2003-12-11 WO disclosed
EP-0780452-B1 Aqueous paint TOYO SEIKAN KAISHA LTD (JP) 2002-03-06 EP disclosed
US-5763507-A EPOXY ACRYLATE RESIN TOYO SEIKAN KAISHA, LTD. (JP) 1998-06-09 US disclosed
EP-0780452-A2 Aqueous paint TOYO SEIKAN KAISHA LIMITED (JP) 1997-06-25 EP disclosed
EP-0414160-B1 Process for preparing advanced epoxy resins DOW CHEMICAL CO (US) 1996-09-11 EP disclosed
US-5310854-A Solvent, coatings for beverage cans THE DOW CHEMICAL COMPANY (US) 1994-05-10 US disclosed
WO-1993004122-A1 POLYESTER COMPOSITIONS CONTAINING PHOSPHONIUM COMPOUNDS THE DOW CHEMICAL COMPANY (US) 1993-03-04 WO disclosed
EP-0414160-A2 Process for preparing advanced epoxy resins THE DOW CHEMICAL COMPANY (US) 1991-02-27 EP disclosed
US-4933420-A Epoxy resins containing phosphonium catalysts THE DOW CHEMICAL COMPANY (US) 1990-06-12 US disclosed
EP-0360195-A2 Epoxy resins containing phosphonium catalysts THE DOW CHEMICAL COMPANY (US) 1990-03-28 EP disclosed