SCHEMBL6062151

SCHEMBL6062151

COc1ccc(F)c(Bc2c(F)cc(F)c(OC)c2F)c1F

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TUBB1 Q9H4B7 11/20 0.38
ALDH1A1 P00352 1/20 0.33
NFE2L2 Q16236 1/20 0.33
LMNA P02545 1/20 0.33
MAPK1 P28482 1/20 0.33
HTT P42858 1/20 0.33
RAB9A P51151 1/20 0.33
TUBB4A P04350 4/20 0.31
TUBB P07437 4/20 0.31
TUBA3C P0DPH7 4/20 0.31
TUBA1B P68363 4/20 0.31
TUBA4A P68366 4/20 0.31
TUBB4B P68371 4/20 0.31
TUBB3 Q13509 4/20 0.31
TUBB2A Q13885 4/20 0.31
TUBB8 Q3ZCM7 4/20 0.31
TUBA3E Q6PEY2 4/20 0.31
TUBA1A Q71U36 4/20 0.31
TUBA1C Q9BQE3 4/20 0.31
TUBB6 Q9BUF5 4/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6063351 0.89 TUBB1 (0.41) TUBB1ALDH1A1NFE2L2LMNAMAPK1
SCHEMBL6063456 0.87 TUBB1 (0.44) TUBB1ALDH1A1NFE2L2LMNAMAPK1
SCHEMBL5356516 0.86 PDGFRB (0.30)
SCHEMBL5355583 0.86 TUBB1 (0.43) TUBB1NFE2L2LMNAMAPK1HTT
SCHEMBL6063832 0.85 TUBB1 (0.45) TUBB1ALDH1A1NFE2L2LMNAMAPK1
SCHEMBL6063568 0.84 TUBB1 (0.30) TUBB1
SCHEMBL5366348 0.84 TUBB1 (0.40) TUBB1ALDH1A1NFE2L2LMNAMAPK1
SCHEMBL6062192 0.84 TUBB1 (0.35) TUBB1HTT
SCHEMBL6062201 0.84 TUBB1 (0.35) TUBB1ALDH1A1
SCHEMBL6063375 0.83 TUBB1 (0.37) TUBB1ALDH1A1NFE2L2LMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060264320-A1 Hydrophobization and silica for supported catalyst RODRIGUEZ GEORGE 2006-11-23 US disclosed