SCHEMBL6062852

SCHEMBL6062852

COc1cc(F)c(F)c(Bc2c(F)ccc(C)c2F)c1F

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TUBB1 Q9H4B7 5/20 0.39
LMNA P02545 1/20 0.31
KDM1A O60341 1/20 0.31
PTGS2 P35354 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6062413 0.89 TUBB1 (0.44) TUBB1LMNAKDM1APTGS2
SCHEMBL6062526 0.87 TUBB1 (0.42) TUBB1LMNAPTGS2
SCHEMBL6061879 0.85
SCHEMBL5357310 0.85 TUBB1 (0.43) TUBB1LMNAKDM1A
SCHEMBL6063832 0.83 TUBB1 (0.45) TUBB1LMNAKDM1A
SCHEMBL6063075 0.83 TUBB1 (0.42) TUBB1LMNAKDM1A
SCHEMBL5345388 0.83 TUBB1 (0.35) TUBB1
SCHEMBL6062334 0.81
SCHEMBL5351315 0.80 TUBB1 (0.38) TUBB1KDM1A
SCHEMBL6062923 0.80 TUBB1 (0.38) TUBB1KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060264320-A1 Hydrophobization and silica for supported catalyst RODRIGUEZ GEORGE 2006-11-23 US disclosed