Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CXCL12 | P48061 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 2/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.31 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 2/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.31 |
| ▸ | CCND1 | P24385 | 2/20 | 0.31 |
| ▸ | CDK2 | P24941 | 2/20 | 0.31 |
| ▸ | CCND3 | P30281 | 2/20 | 0.31 |
| ▸ | KDR | P35968 | 2/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5576185 | 0.83 | POLB (0.40) | POLBCXCL12MAOBIDO1APP | |
| SCHEMBL8038380 | 0.80 | KDM4E (0.33) | KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL5537163 | 0.79 | KDM4E (0.33) | KDM4EMAPT | |
| SCHEMBL6292711 | 0.77 | — | — | |
| SCHEMBL19718138 | 0.76 | SETD7 (0.39) | GAAALDH1A1KDM4EMAPTRAB9A | |
| SCHEMBL11018793 | 0.72 | — | — | |
| SCHEMBL8986492 | 0.72 | — | — | |
| SCHEMBL613742 | 0.72 | — | — | |
| SCHEMBL268108 | 0.72 | — | — | |
| SCHEMBL2951402 | 0.72 | PDE4A (0.36) | GAAGFERALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8114350-B1 | Sensors for detecting substances indicative of stroke, ischemia, infection or inflammation | N2ITIVE1 INNOVATIONS | 2012-02-14 | — | — | US | disclosed |
| US-7769420-B2 | Sensors for detecting substances indicative of stroke, ischemia, or myocardial infarction | SILVER JAMES H | 2010-08-03 | — | — | US | disclosed |
| US-20060079740-A1 | Sensors for detecting substances indicative of stroke, ischemia, or myocardial infarction | SILVER JAMES H | 2006-04-13 | — | — | US | disclosed |