SCHEMBL6063386

SCHEMBL6063386

C=CCC([CH][SiH3])(CC=C)CCCC

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.37
ALDH1A1 P00352 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20718873 0.76 TSHR (0.41) TSHRALDH1A1
SCHEMBL9659876 0.75 TSHR (0.34) TSHRALDH1A1
SCHEMBL6063926 0.73 TSHR (0.40) TSHRALDH1A1
SCHEMBL23131883 0.72 TSHR (0.43) TSHRALDH1A1
SCHEMBL30697923 0.71 TSHR (0.41) TSHRALDH1A1
SCHEMBL11597720 0.70 TSHR (0.42) TSHRALDH1A1
SCHEMBL27756430 0.69 TSHR (0.39) TSHRALDH1A1
SCHEMBL8554827 0.68 TSHR (0.40) TSHRALDH1A1
SCHEMBL8993592 0.68 TSHR (0.40) TSHRALDH1A1
SCHEMBL3260350 0.68 TSHR (0.40) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0963996-B9 Transition metal compound, catalyst component and catalyst for olefin polymerization and process for the preparation of alpha-olefin polymer JAPAN POLYCHEM CORP (JP) 2006-09-06 EP disclosed
EP-0963996-B1 Transition metal compound, catalyst component and catalyst for olefin polymerization and process for the preparation of alpha-olefin polymer JAPAN POLYCHEM CORP (JP) 2006-05-24 EP disclosed
US-6218558-B1 BRIDGED OXYGEN-, NITROGEN- OR SULFUR-CONTAINING METALLOCENE CATALYST CONTAINING AT LEAST CYCLOPENTADIENE RING FUSED TO A C7-10 RING JAPAN POLYCHEM CORPORATION (JP) 2001-04-17 US disclosed
EP-0963996-A2 Novel transition metal compound, catalyst component for olefin polymerization and process for the preparation of alpha-olefin polymer Japan Polychem Corporation (JP) 1999-12-15 EP disclosed