SCHEMBL6063504

SCHEMBL6063504

C=CCC[Si](C)(CCCC)CCCC

nearest known ligand 0.52

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.52
ALDH1A1 P00352 1/20 0.52
FAAH O00519 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6063962 0.85 TSHR (0.48) TSHRALDH1A1
SCHEMBL231380 0.84 TSHR (0.42) TSHRALDH1A1
SCHEMBL10843332 0.82 TSHR (0.70) TSHRALDH1A1FAAH
SCHEMBL10842911 0.82 TSHR (0.70) TSHRALDH1A1FAAH
SCHEMBL10843200 0.82 TSHR (0.70) TSHRALDH1A1FAAH
SCHEMBL10842401 0.82 TSHR (0.70) TSHRALDH1A1FAAH
SCHEMBL10841703 0.82 TSHR (0.70) TSHRALDH1A1FAAH
SCHEMBL6063997 0.81 TSHR (0.52) TSHRALDH1A1FAAH
SCHEMBL2954862 0.79 TSHR (0.48) TSHRALDH1A1
SCHEMBL3676139 0.79 TSHR (0.43) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016164565-A1 TRANS-CYCLOHEPTENES AND HETERO-TRANS-CYCLOHEPTENES FOR BIOORTHOGONAL COUPLING UNIVERSITY OF DELAWARE (US) 2016-10-13 WO disclosed
US-7015292-B2 Silicon-containing olefin copolymer, crosslinkable rubber composition thereof, and use thereof MITSUI CHEMICALS, INC. (JP) 2006-03-21 US disclosed
US-20050038214-A1 Silicon-containing olefin copolymer, crosslinkable rubber composition thereof, and use thereof MITSUI CHEMICALS, INC. (JP) 2005-02-17 US disclosed