Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 10/20 | 0.56 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.55 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.48 |
| ▸ | THRA | P10827 | 6/20 | 0.47 |
| ▸ | THRB | P10828 | 6/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.46 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12394633 | 0.92 | FFAR1 (0.49) | FFAR1FFAR4SUCNR1MRGPRX4THRA | |
| SCHEMBL2352559 | 0.88 | FFAR1 (0.48) | FFAR1FFAR4SUCNR1MRGPRX4THRA | |
| SCHEMBL2346143 | 0.87 | FFAR1 (0.71) | FFAR1FFAR4THRATHRBAKR1B1 | |
| SCHEMBL2349126 | 0.84 | FFAR1 (0.67) | FFAR1FFAR4THRATHRBESR1 | |
| SCHEMBL6063654 | 0.80 | FFAR1 (0.56) | FFAR1FFAR4THRATHRBAKR1B1 | |
| SCHEMBL2354346 | 0.80 | FFAR1 (0.63) | FFAR1FFAR4THRATHRBESR1 | |
| SCHEMBL2350889 | 0.80 | FFAR1 (0.67) | FFAR1FFAR4THRATHRBAKR1B1 | |
| SCHEMBL2350861 | 0.80 | FFAR1 (0.76) | FFAR1FFAR4THRATHRB | |
| SCHEMBL2346105 | 0.80 | FFAR1 (0.64) | FFAR1FFAR4THRATHRBESR1 | |
| SCHEMBL2353744 | 0.80 | FFAR1 (0.64) | FFAR1FFAR4THRATHRBESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1688138-A1 | RECEPTOR FUNCTION REGULATING AGENT | Takeda Pharmaceutical Company Limited (JP) | 2006-08-09 | — | — | EP | disclosed |