Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | PREP | P48147 | 1/20 | 0.31 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6062357 | 1.00 | DPP4 (0.36) | DPP4GFERPREPAGTR2KDM4E | |
| SCHEMBL6062214 | 0.92 | DPP4 (0.38) | DPP4GFERAGTR2KDM4ELMNA | |
| SCHEMBL6063409 | 0.91 | DPP4 (0.35) | DPP4GFERAGTR2KDM4ELMNA | |
| SCHEMBL6474079 | 0.91 | DPP4 (0.35) | DPP4GFERAGTR2KDM4ELMNA | |
| SCHEMBL6479927 | 0.91 | DPP4 (0.35) | DPP4GFERAGTR2KDM4ELMNA | |
| SCHEMBL6062512 | 0.89 | DPP8 (0.32) | — | |
| SCHEMBL1728832 | 0.84 | DPP4 (0.35) | DPP4GFER | |
| SCHEMBL1728242 | 0.84 | DPP4 (0.35) | DPP4GFER | |
| SCHEMBL1728385 | 0.84 | DPP4 (0.35) | DPP4GFER | |
| SCHEMBL6063359 | 0.83 | TOP2A (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7008957-B2 | Bicyclic cyanoheterocycles, process for their preparation and their use as medicaments | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2006-03-07 | — | — | US | disclosed |