Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.51 |
| ▸ | GSK3B | P49841 | 2/20 | 0.50 |
| ▸ | BACE1 | P56817 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6063634 | 1.00 | NR1H4 (0.51) | NR1H4GSK3BBACE1KDM4EGAA | |
| SCHEMBL14498299 | 0.86 | NR1H4 (0.58) | NR1H4GSK3BBACE1KDM4EGAA | |
| SCHEMBL6061638 | 0.86 | NR1H4 (0.58) | NR1H4GSK3BBACE1KDM4EGAA | |
| SCHEMBL6023595 | 0.82 | AKR1C3 (0.43) | ABCG2MEN1ALDH1A1KMT2A | |
| SCHEMBL14498298 | 0.81 | NR1H4 (0.55) | NR1H4GSK3BBACE1KDM4EGAA | |
| SCHEMBL5606809 | 0.80 | NR1H4 (0.60) | NR1H4GSK3BBACE1KDM4EGAA | |
| SCHEMBL5606805 | 0.80 | NR1H4 (0.60) | NR1H4GSK3BBACE1KDM4EGAA | |
| SCHEMBL5606671 | 0.80 | NR1H4 (0.56) | NR1H4GSK3BBACE1KDM4EGAA | |
| SCHEMBL5606669 | 0.80 | NR1H4 (0.56) | NR1H4GSK3BBACE1KDM4EGAA | |
| SCHEMBL5607889 | 0.79 | NR1H4 (0.59) | NR1H4GSK3BBACE1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1687250-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE 3-(4-HYDROXYPHENYL)PROPIONIC ACIDS | Takasago International Corporation (JP) | 2006-08-09 | — | — | EP | disclosed |
| WO-2005051882-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE 3-(4-HYDROXYPHENYL)PROPIONIC ACIDS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2005-06-09 | — | — | WO | disclosed |