SCHEMBL6063689

SCHEMBL6063689

C[C@@H](O)[C@@H](N)CO

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3766608 1.00
SCHEMBL26050830 1.00
SCHEMBL1704657 1.00
SCHEMBL606176 1.00
SCHEMBL155525 1.00
SCHEMBL18622742 1.00
SCHEMBL1620911 1.00
SCHEMBL11972561 1.00
Hydrochloric Acid SCHEMBL30403161 0.97
Hydrochloric Acid SCHEMBL19642540 0.97

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12116343-B2 Inhibitors of APOL1 and methods of using same VERTEX PHARMACEUTICALS INCORPORATED (US) 2024-10-15 US disclosed
US-20240218041-A1 MOLECULAR DESIGN OF GLUCOSE SENSORS IN GLUCOSE-RESPONSIVE INSULIN ANALOGUES NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2024-07-04 US disclosed
EP-4334338-A1 MOLECULAR DESIGN OF GLUCOSE SENSORS IN GLUCOSE-RESPONSIVE INSULIN ANALOGUES The Trustees of Indiana University (US) 2024-03-13 EP disclosed
US-20230399373-A1 MOLECULAR DESIGNS OF GLUCOSE-RESPONSIVE AND GLUCOSE-CLEAVABLE INSULIN ANALOGUES THE TRUSTEES OF INDIANA UNIVERSITY 2023-12-14 US disclosed
EP-4232464-A1 MOLECULAR DESIGNS OF GLUCOSE-RESPONSIVE AND GLUCOSE-CLEAVABLE INSULIN ANALOGUES The Trustees of Indiana University (US) 2023-08-30 EP disclosed
WO-2023154344-A1 2-METHYL-4',5'-DIHYDROSPIRO[PIPERIDINE-4,7'-THIENO[2,3-C]PYRAN] DERIVATIVES AS INHIBITORS OF APOL1 AND METHODS OF USING SAME VERTEX PHARMACEUTICALS INCORPORATED (US) 2023-08-17 WO disclosed
US-20230014907-A1 INHIBITORS OF APOL1 AND METHODS OF USING SAME VERTEX PHARMACEUTICALS INCORPORATED 2023-01-19 US disclosed
WO-2022235691-A1 MOLECULAR DESIGN OF GLUCOSE SENSORS IN GLUCOSE-RESPONSIVE INSULIN ANALOGUES THE TRUSTEES OF INDIANA UNIVERSITY (US) 2022-11-10 WO disclosed
US-20220340523-A1 INHIBITORS OF APOL1 AND METHODS OF USING SAME VERTEX PHARMACEUTICALS INCORPORATED 2022-10-27 US disclosed
US-20220153752-A1 DIFLUOROMETHYL-AMINOPYRIDINES AND DIFLUOROMETHYL-AMINOPYRIMIDINES TORQUR AG (CH) 2022-05-19 US disclosed
US-8865894-B2 Oxazolidin-2-one compounds and uses thereof NOVARTIS AG (CH) 2014-10-21 US disclosed
WO-2013124826-A1 OXAZOLIDIN- 2 -ONE COMPOUNDS AND USES THEREOF AS PI3KS INHIBITORS NOVARTIS AG (CH) 2013-08-29 WO disclosed
US-20130225574-A1 OXAZOLIDIN-2-ONE COMPOUNDS AND USES THEREOF NOVARTIS AG (CH) 2013-08-29 US disclosed
US-20130225574-A1 OXAZOLIDIN-2-ONE COMPOUNDS AND USES THEREOF NOVARTIS AG (CH) 2013-08-29 US disclosed
US-8450342-B2 Perharidines as CDK inhibitors CENTRE NATIONALE DE LA RECHERCHE SCIENTIFIQUE (FR) 2013-05-28 US disclosed
US-8450342-B2 Perharidines as CDK inhibitors CENTRE NATIONALE DE LA RECHERCHE SCIENTIFIQUE (FR) 2013-05-28 US disclosed
US-20120245124-A1 TRPV3 Modulators ABBOTT LABORATORIES (US) 2012-09-27 US disclosed
WO-2011135141-A1 MODIFIED OLIGONUCLEOTIDES AS REGULATORS OF GENE EXPRESSION CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (ES) 2011-11-03 WO disclosed
US-20060147985-A1 Methods and compositions for monitoring polymer array synthesis AFFYMETRIX, INC. (US) 2006-07-06 US disclosed
US-7026114-B1 Methods and compositions for monitoring polymer array synthesis AFFYMETRIX, INC. (US) 2006-04-11 US disclosed