SCHEMBL6063728

SCHEMBL6063728

COCCOc1cccc(COc2ccc(CCC(=O)O)cc2F)c1

nearest known ligand 0.58

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 16/20 0.58
FFAR4 Q5NUL3 8/20 0.58
PPARD Q03181 2/20 0.50
PPARA Q07869 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12394722 0.92 FFAR1 (0.51) FFAR1FFAR4PPARDPPARA
SCHEMBL6063524 0.89 FFAR1 (0.60) FFAR1FFAR4PPARD
SCHEMBL6063764 0.88 FFAR1 (0.61) FFAR1FFAR4PPARD
SCHEMBL2348819 0.88 FFAR1 (0.50) FFAR1FFAR4PPARDPPARA
SCHEMBL2351737 0.87 FFAR1 (0.59) FFAR1FFAR4PPARDPPARA
SCHEMBL2346682 0.86 FFAR1 (0.59) FFAR1FFAR4PPARDPPARA
SCHEMBL3967976 0.85 FFAR4 (0.51) FFAR1FFAR4PPARDPPARA
SCHEMBL3668051 0.85 FFAR1 (0.60) FFAR1FFAR4PPARDPPARA
SCHEMBL6062739 0.85 FFAR4 (0.61) FFAR1FFAR4
SCHEMBL2349311 0.84 FFAR1 (0.76) FFAR1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1688138-A1 RECEPTOR FUNCTION REGULATING AGENT Takeda Pharmaceutical Company Limited (JP) 2006-08-09 EP disclosed