Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 11/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.51 |
| ▸ | THRA | P10827 | 6/20 | 0.46 |
| ▸ | THRB | P10828 | 6/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12394632 | 0.92 | FFAR1 (0.43) | FFAR1FFAR4THRATHRBESR1 | |
| SCHEMBL2355921 | 0.89 | FFAR1 (0.43) | FFAR1FFAR4THRATHRBCYP4F2 | |
| SCHEMBL2346143 | 0.84 | FFAR1 (0.71) | FFAR1FFAR4THRATHRBESR1 | |
| SCHEMBL6062477 | 0.83 | FFAR1 (0.53) | FFAR1FFAR4THRATHRBESR1 | |
| SCHEMBL2346716 | 0.81 | FFAR1 (0.56) | FFAR1FFAR4THRATHRBESR1 | |
| SCHEMBL6063654 | 0.81 | FFAR1 (0.56) | FFAR1FFAR4THRATHRBESR1 | |
| SCHEMBL2349126 | 0.81 | FFAR1 (0.67) | FFAR1FFAR4THRATHRBESR1 | |
| SCHEMBL2354346 | 0.79 | FFAR1 (0.63) | FFAR1FFAR4THRATHRBESR1 | |
| SCHEMBL2346105 | 0.79 | FFAR1 (0.64) | FFAR1FFAR4THRATHRBESR1 | |
| SCHEMBL2350861 | 0.79 | FFAR1 (0.76) | FFAR1FFAR4THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1688138-A1 | RECEPTOR FUNCTION REGULATING AGENT | Takeda Pharmaceutical Company Limited (JP) | 2006-08-09 | — | — | EP | disclosed |