SCHEMBL6063891

SCHEMBL6063891

[SiH3]C(Cl)(Cl)CCC1CC2C=CC1C2

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.38
ALDH1A1 P00352 3/20 0.38
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
HTT P42858 1/20 0.34
TSHR P16473 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C19 P33261 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6064454 0.89 KDM4E (0.36) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL6064147 0.88 KDM4E (0.35) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL6063867 0.86 KDM4E (0.34) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL6063489 0.86 KDM4E (0.34) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL6064170 0.86 KDM4E (0.34) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL6062812 0.83 KDM4E (0.37) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL6063362 0.81 KDM4E (0.40) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL6062504 0.81 KDM4E (0.38) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL6063200 0.77 KDM4E (0.38) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL6063790 0.77 KDM4E (0.41) KDM4EALDH1A1MEN1KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7015292-B2 Silicon-containing olefin copolymer, crosslinkable rubber composition thereof, and use thereof MITSUI CHEMICALS, INC. (JP) 2006-03-21 US disclosed
US-20050038214-A1 Silicon-containing olefin copolymer, crosslinkable rubber composition thereof, and use thereof MITSUI CHEMICALS, INC. (JP) 2005-02-17 US disclosed
EP-0388005-A2 Selective monohydrosilation of vinyl and ethynyl functional norbornenes and curable products produced thereby LOCTITE CORPORATION (US) 1990-09-19 EP disclosed
EP-0388028-A2 Curable norbornenyl functional silicone formulations LOCTITE CORPORATION (US) 1990-09-19 EP disclosed