Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8756704 | 1.00 | TSHR (0.48) | TSHRALDH1A1ABCC4MAPTLMNA | |
| SCHEMBL6037321 | 1.00 | TSHR (0.48) | TSHRALDH1A1ABCC4MAPTLMNA | |
| SCHEMBL6064292 | 1.00 | TSHR (0.48) | TSHRALDH1A1ABCC4MAPTLMNA | |
| SCHEMBL28499206 | 1.00 | TSHR (0.48) | TSHRALDH1A1ABCC4MAPTLMNA | |
| SCHEMBL6037333 | 1.00 | TSHR (0.48) | TSHRALDH1A1ABCC4MAPTLMNA | |
| SCHEMBL6037439 | 1.00 | TSHR (0.48) | TSHRALDH1A1ABCC4MAPTLMNA | |
| SCHEMBL6063626 | 1.00 | TSHR (0.48) | TSHRALDH1A1ABCC4MAPTLMNA | |
| SCHEMBL28494261 | 1.00 | TSHR (0.48) | TSHRALDH1A1ABCC4MAPTLMNA | |
| SCHEMBL6037293 | 1.00 | TSHR (0.48) | TSHRALDH1A1ABCC4MAPTLMNA | |
| SCHEMBL3885707 | 0.98 | TSHR (0.44) | TSHRALDH1A1ABCC4MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7015292-B2 | Silicon-containing olefin copolymer, crosslinkable rubber composition thereof, and use thereof | MITSUI CHEMICALS, INC. (JP) | 2006-03-21 | — | — | US | disclosed |
| US-20050038214-A1 | Silicon-containing olefin copolymer, crosslinkable rubber composition thereof, and use thereof | MITSUI CHEMICALS, INC. (JP) | 2005-02-17 | — | — | US | disclosed |