SCHEMBL6064045

SCHEMBL6064045

CO[SiH2]CCC1CC2C=CC1C2

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 10/20 0.44
ALDH1A1 P00352 5/20 0.44
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
HTT P42858 1/20 0.36
TSHR P16473 1/20 0.36
POLB P06746 1/20 0.34
ALOX15 P16050 1/20 0.34
TDP1 Q9NUW8 1/20 0.31
MAPT P10636 1/20 0.30
PKM P14618 1/20 0.30
MAPK1 P28482 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6064468 0.83 KDM4E (0.45) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL6064195 0.81 KDM4E (0.42) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL15805497 0.79 KDM4E (0.47) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL6064260 0.78 KDM4E (0.41) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL31031258 0.77 KDM4E (0.36) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL6063138 0.77 KDM4E (0.40) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL6063124 0.77 KDM4E (0.40) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL1012047 0.76 KDM4E (0.48) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL5701506 0.76 KDM4E (0.36) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL4787657 0.76 KDM4E (0.43) KDM4EALDH1A1MEN1KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110251357-A1 ULTRAVIOLET TRANSMISSIVE POLYHEDRAL SILSESQUIOXANE POLYMERS PANASONIC ELECTRIC WORKS CO., LTD. 2011-10-13 US disclosed
US-7015292-B2 Silicon-containing olefin copolymer, crosslinkable rubber composition thereof, and use thereof MITSUI CHEMICALS, INC. (JP) 2006-03-21 US disclosed
US-20050038214-A1 Silicon-containing olefin copolymer, crosslinkable rubber composition thereof, and use thereof MITSUI CHEMICALS, INC. (JP) 2005-02-17 US disclosed