Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | TERT | O14746 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5840221 | 0.91 | MAPT (0.54) | MAPTHTTHTR1AADRA1DADRA1A | |
| SCHEMBL814598 | 0.84 | MAPT (0.48) | MAPTHTTHTR1AADRA1DADRA1A | |
| SCHEMBL814427 | 0.82 | MAPT (0.46) | MAPTHTTHTR1AADRA1DADRA1A | |
| SCHEMBL814335 | 0.82 | MAPT (0.46) | MAPTHTTHTR1AADRA1DADRA1A | |
| SCHEMBL814019 | 0.82 | MAPT (0.46) | MAPTHTTHTR1AADRA1DADRA1A | |
| SCHEMBL814657 | 0.82 | MAPT (0.46) | MAPTHTTHTR1AADRA1DADRA1A | |
| SCHEMBL816147 | 0.82 | MAPT (0.46) | MAPTHTTHTR1AADRA1DADRA1A | |
| SCHEMBL5838710 | 0.81 | MAPT (0.44) | MAPTHTTHTR1AADRA1DADRA1A | |
| SCHEMBL5840516 | 0.81 | MAPT (0.44) | MAPTHTTHTR1AADRA1DADRA1A | |
| SCHEMBL1259718 | 0.80 | MAPT (0.42) | MAPTHTTHTR1BCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1641842-A2 | POLYMERIZATION AND OLIGOMERIZATION CATALYST WITH TRIDENTATE OR TETRADENTATE LIGAND | Exxonmobil Chemical Patents Inc. (US) | 2006-04-05 | — | — | EP | disclosed |
| WO-2004106390-A2 | POLYMERIZATION AND OLIGOMERIZATION CATALYST WITH TRIDENTATE OR TETRADENTATE LIGAND | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-12-09 | — | — | WO | disclosed |
| US-4479962-A | CARDIOTONIC AGENTS | BOEHRINGER MANNHEIM GMBH (DE) | 1984-10-30 | — | — | US | disclosed |
| EP-0071950-A1 | Heteroarylpropanol amines, process for preparing them and medicines containing these compounds | Roche Diagnostics GmbH (DE) | 1983-02-16 | — | — | EP | disclosed |