Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 20/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2726090 | 0.96 | TRPV1 (0.69) | TRPV1 | |
| SCHEMBL5449613 | 0.87 | TRPV1 (0.69) | TRPV1 | |
| SCHEMBL2731788 | 0.84 | TRPV1 (0.70) | TRPV1 | |
| SCHEMBL2724027 | 0.83 | TRPV1 (0.69) | TRPV1 | |
| SCHEMBL2733006 | 0.83 | TRPV1 (0.69) | TRPV1 | |
| SCHEMBL2731998 | 0.80 | TRPV1 (0.62) | TRPV1 | |
| SCHEMBL5441567 | 0.80 | TRPV1 (0.65) | TRPV1 | |
| SCHEMBL6065428 | 0.80 | TRPV1 (0.62) | TRPV1 | |
| SCHEMBL4027832 | 0.79 | TRPV1 (0.64) | TRPV1 | |
| SCHEMBL6065412 | 0.78 | TRPV1 (0.51) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660455-A1 | FUSED AZABICYCLIC COMPOUNDS THAT INHIBIT VANILLOID RECEPTOR SUBTYPE 1 (VR1) RECEPTOR | ABBOTT LABORATORIES (US) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005016890-A1 | FUSED AZABICYCLIC COMPOUNDS THAT INHIBIT VANILLOID RECEPTOR SUBTYPE 1 (VR1) RECEPTOR | ABBOTT LABORATORIES (US) | 2005-02-24 | — | — | WO | disclosed |