Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14983 | 0.96 | TSHR (0.43) | TSHRALDH1A1THRB | |
| Methacrylic Acid SCHEMBL5984544 | 0.94 | TSHR (0.39) | TSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL129148 | 0.94 | TSHR (0.42) | TSHRALDH1A1THRB | |
| Ammonia Solution, Strong SCHEMBL5702351 | 0.94 | TSHR (0.42) | TSHRALDH1A1THRB | |
| Methyl Alcohol SCHEMBL21326729 | 0.94 | TSHR (0.42) | TSHRALDH1A1THRB | |
| Bromide SCHEMBL1302921 | 0.94 | TSHR (0.42) | TSHRALDH1A1THRB | |
| Fluoride SCHEMBL1303213 | 0.94 | TSHR (0.42) | TSHRALDH1A1THRB | |
| Iodide SCHEMBL1302038 | 0.94 | TSHR (0.42) | TSHRALDH1A1THRB | |
| Acetic Acid SCHEMBL18298040 | 0.93 | TSHR (0.36) | TSHRALDH1A1 | |
| Chloromethane SCHEMBL127391 | 0.92 | TSHR (0.41) | TSHRALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110101877-B | Ultrasonic contrast agent capable of being activated under acidic pH condition of tumor microenvironment as well as preparation method and application thereof | 中山大学 | 2020-12-04 | — | — | CN | claimed |
| JP-2006500254-A | — | — | 2006-01-05 | — | — | JP | claimed |
| EP-1545894-A1 | COMPOSITIONS FOR INK-JET INK-RECEPTOR SHEETS | 3M Innovative Properties Company (US) | 2005-06-29 | — | — | EP | claimed |
| WO-2004028821-A1 | COMPOSITIONS FOR INK-JET INK-RECEPTOR SHEETS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2004-04-08 | — | — | WO | claimed |
| US-20040059045-A1 | Water resistant inkjet photo paper | 3M INNOVATIVE PROPERTIES COMPANY | 2004-03-25 | — | — | US | claimed |
| EP-0213317-B1 | BASE-CATALYZED, LOW TEMPERATURE SELF-CROSSLINKING POLYMERS | National Starch and Chemical Investment Holding Corporation (US) | 1991-12-04 | — | — | EP | claimed |
| US-4788267-A | CONTAINING HALOHYDRIN MONOMER AND AMINE SALT MONOMER | NATIONAL STARCH AND CHEMICAL CORPORATION (US) | 1988-11-29 | — | — | US | claimed |
| EP-0213317-A2 | Base-catalyzed, low temperature self-crosslinking polymers | National Starch and Chemical Investment Holding Corporation (US) | 1987-03-11 | — | — | EP | claimed |
| US-4343729-A | Organic pigments | HERCULES INCORPORATED (US) | 1982-08-10 | — | — | US | claimed |
| US-4293666-A | GRAFT POLYMERIZING UNSATURATED MONOMER ONTO WATER SOLUBLE CATIONIC PREPOLYMER | HERCULES INCORPORATED (US) | 1981-10-06 | — | — | US | claimed |
| US-4281082-A | FILLERS FOR PAPER, GRAFT POLYMERS OF CATIONIC AMINE MONOMERS | HERCULES INCORPORATED (US) | 1981-07-28 | — | — | US | claimed |
| CN-115232528-A | Super-hydrophilic antibacterial coating sol and preparation method and application thereof | 泉州师范学院 | 2022-10-25 | — | — | CN | disclosed |
| CN-115181468-A | Super-hydrophilic self-cleaning coating sol and preparation method and application thereof | 泉州师范学院 | 2022-10-14 | — | — | CN | disclosed |
| CN-110101877-B | Ultrasonic contrast agent capable of being activated under acidic pH condition of tumor microenvironment as well as preparation method and application thereof | 中山大学 | 2020-12-04 | — | — | CN | disclosed |
| CN-110101877-B | Ultrasonic contrast agent capable of being activated under acidic pH condition of tumor microenvironment as well as preparation method and application thereof | 中山大学 | 2020-12-04 | — | — | CN | disclosed |
| US-4293667-A | GRAFT POLYMERIZING UNSATURATED MONOMER ONTO WATER SOLUBLE CATIONIC PREPOLYMER | HERCULES INCORPORATED (US) | 1981-10-06 | — | — | US | disclosed |
| US-4282060-A | A CATIONIC GRAFT ADDITION POLYMER; PAPER FILLERS; OPACITY | HERCULES INCORPORATED (US) | 1981-08-04 | — | — | US | disclosed |
| US-4281082-A | FILLERS FOR PAPER, GRAFT POLYMERS OF CATIONIC AMINE MONOMERS | HERCULES INCORPORATED (US) | 1981-07-28 | — | — | US | disclosed |
| US-4248939-A | OVERCOATING WITH AN ORGANIC PIGMENT WHICH IS A GRAFT POLYMER OF UNSATURATED MONOMERS AND PREPOLYMERS | HERCULES INCORPORATED (US) | 1981-02-03 | — | — | US | disclosed |
| US-4235982-A | POLYMERIC FILLERS FOR PAPER | HERCULES, INCORPORATED (US) | 1980-11-25 | — | — | US | disclosed |