Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 2/20 | 0.55 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.55 |
| ▸ | TEAD1 | P28347 | 3/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 2/20 | 0.48 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.46 |
| ▸ | IDH2 | P48735 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3816081 | 0.95 | CARM1 (0.59) | CARM1PRMT6TEAD1SLC6A4SLC6A2 | |
| Methylene Chloride SCHEMBL27890329 | 0.91 | CARM1 (0.56) | CARM1PRMT6TEAD1SLC6A4SLC6A2 | |
| SCHEMBL23200173 | 0.88 | CARM1 (0.63) | CARM1PRMT6TEAD1ALDH1A1MEN1 | |
| SCHEMBL4244332 | 0.88 | CARM1 (0.63) | CARM1PRMT6TEAD1ALDH1A1MEN1 | |
| SCHEMBL2470940 | 0.85 | CARM1 (0.66) | CARM1PRMT6TEAD1HTR2CALDH1A1 | |
| SCHEMBL29456933 | 0.85 | CARM1 (0.66) | CARM1PRMT6TEAD1HTR2CALDH1A1 | |
| Hydrochloric Acid SCHEMBL30117154 | 0.83 | CARM1 (0.64) | CARM1PRMT6TEAD1ALDH1A1MEN1 | |
| SCHEMBL30334887 | 0.81 | CARM1 (0.57) | CARM1PRMT6TEAD1SLC6A4MEN1 | |
| SCHEMBL24168829 | 0.81 | CARM1 (0.57) | CARM1PRMT6TEAD1SLC6A4MEN1 | |
| SCHEMBL31336978 | 0.80 | SLC6A4 (0.48) | CARM1PRMT6SLC6A4SLC6A2HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660455-A1 | FUSED AZABICYCLIC COMPOUNDS THAT INHIBIT VANILLOID RECEPTOR SUBTYPE 1 (VR1) RECEPTOR | ABBOTT LABORATORIES (US) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005016890-A1 | FUSED AZABICYCLIC COMPOUNDS THAT INHIBIT VANILLOID RECEPTOR SUBTYPE 1 (VR1) RECEPTOR | ABBOTT LABORATORIES (US) | 2005-02-24 | — | — | WO | disclosed |