Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4448957 | 1.00 | NPSR1 (0.38) | NPSR1HCAR2ALDH1A1MAPT | |
| SCHEMBL4448959 | 1.00 | NPSR1 (0.38) | NPSR1HCAR2ALDH1A1MAPT | |
| SCHEMBL4448960 | 1.00 | NPSR1 (0.38) | NPSR1HCAR2ALDH1A1MAPT | |
| SCHEMBL6067588 | 1.00 | NPSR1 (0.38) | NPSR1HCAR2ALDH1A1MAPT | |
| SCHEMBL4983717 | 0.88 | NPSR1 (0.40) | NPSR1HCAR2ALDH1A1MAPT | |
| SCHEMBL4448271 | 0.88 | NPSR1 (0.40) | NPSR1HCAR2ALDH1A1MAPT | |
| SCHEMBL4983712 | 0.88 | NPSR1 (0.40) | NPSR1HCAR2ALDH1A1MAPT | |
| SCHEMBL4447209 | 0.82 | NPSR1 (0.38) | NPSR1HCAR2ALDH1A1MAPT | |
| SCHEMBL4447215 | 0.82 | NPSR1 (0.38) | NPSR1HCAR2ALDH1A1MAPT | |
| SCHEMBL4447211 | 0.82 | NPSR1 (0.38) | NPSR1HCAR2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006100606-A2 | PREPARATION OF BETA-AMINO ACID PRECURSORS VIA INDIUM (III) MEDIATED MARKOVNIKOV ADDITION AND KNOEVENAGEL CONDENSATION | WARNER-LAMBERT COMPANY LLC (US) | 2006-09-28 | — | — | WO | disclosed |