Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 5/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PTGIR | P43119 | 2/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6068659 | 0.84 | ADORA2A (0.32) | KMO | |
| SCHEMBL6068838 | 0.84 | MEN1 (0.34) | KMOMAPK1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6068794 | 0.82 | KCNH2 (0.33) | KMOPTGIR | |
| SCHEMBL6068826 | 0.81 | — | — | |
| SCHEMBL6068765 | 0.79 | PTGIR (0.31) | PTGIR | |
| SCHEMBL6068842 | 0.78 | PDE4A (0.33) | KMOMAPK1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5425093 | 0.78 | SMPD3 (0.30) | KMT2A | |
| SCHEMBL6068784 | 0.75 | PTGIR (0.38) | PTGIR | |
| SCHEMBL6068515 | 0.75 | MAPK1 (0.33) | MAPK1OPRM1OPRL1LMNA | |
| SCHEMBL6068670 | 0.74 | MEN1 (0.33) | KMOMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7091350-B2 | Diaminopyrazole derivatives and their use for oxidation dyeing of keratinous fibres | L'OREAL (FR) | 2006-08-15 | — | — | US | disclosed |