Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 20/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6069072 | 0.89 | MAPK14 (0.72) | MAPK14 | |
| SCHEMBL4767834 | 0.87 | MAPK14 (0.76) | MAPK14 | |
| SCHEMBL5773320 | 0.86 | MAPK14 (1.00) | MAPK14 | |
| SCHEMBL5774689 | 0.85 | MAPK14 (0.81) | MAPK14 | |
| SCHEMBL4828259 | 0.85 | MAPK14 (0.76) | MAPK14 | |
| SCHEMBL4762673 | 0.84 | MAPK14 (0.72) | MAPK14 | |
| SCHEMBL5772627 | 0.83 | MAPK14 (0.74) | MAPK14 | |
| SCHEMBL4771276 | 0.81 | MAPK14 (0.71) | MAPK14 | |
| SCHEMBL4769185 | 0.80 | MAPK14 (0.76) | MAPK14 | |
| SCHEMBL4769307 | 0.80 | MAPK14 (1.00) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7005523-B2 | Cycloalkyl-[4-(trifluorophenyl)-oxazol-5yl]-triazolo-pyridines | PFIZER INC. (US) | 2006-02-28 | — | — | US | disclosed |
| US-20040157877-A1 | Cycloalkyl-[4-(trifluorophenyl)-oxazol-5yl]-triazolo-pyridines | PFIZER INC | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157877-A1 | Cycloalkyl-[4-(trifluorophenyl)-oxazol-5yl]-triazolo-pyridines | MAP4K2, MAP3K1, MAP3K5 | MAPK14 39/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.