Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 1.00 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29058172 | 1.00 | KCNH2 (1.00) | KCNH2GPR84CYP19A1 | |
| SCHEMBL29869667 | 1.00 | KCNH2 (1.00) | KCNH2GPR84CYP19A1 | |
| SCHEMBL31246249 | 1.00 | KCNH2 (1.00) | KCNH2GPR84CYP19A1 | |
| SCHEMBL6466826 | 1.00 | KCNH2 (1.00) | KCNH2GPR84CYP19A1 | |
| SCHEMBL28879054 | 1.00 | KCNH2 (1.00) | KCNH2GPR84CYP19A1 | |
| SCHEMBL10790586 | 1.00 | KCNH2 (1.00) | KCNH2GPR84CYP19A1 | |
| SCHEMBL24973117 | 1.00 | KCNH2 (1.00) | KCNH2GPR84CYP19A1 | |
| SCHEMBL6463178 | 1.00 | KCNH2 (1.00) | KCNH2GPR84CYP19A1 | |
| Hydrochloric Acid SCHEMBL26123438 | 0.98 | KCNH2 (0.96) | KCNH2GPR84CYP19A1 | |
| SCHEMBL248521 | 0.98 | KCNH2 (0.95) | KCNH2GPR84CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7026478-B2 | Iron catalyzed cross coupling reactions of aromatic compounds | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2006-04-11 | — | — | US | disclosed |
| US-20050075241-A1 | Catalyst systems of the ziegler-natta type and a method for production thereof | FOTTINGER KLAUS (DE) | 2005-04-07 | — | — | US | disclosed |
| EP-1058696-B1 | DONOR-MODIFIED OLEFIN POLYMERIZATION CATALYSTS | GRACE W R & CO (US) | 2004-04-14 | — | — | EP | disclosed |
| US-20030220498-A1 | Iron catalyzed cross coupling reactions of aromatic compounds | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2003-11-27 | — | — | US | disclosed |
| EP-1326899-A2 | CATALYTIC SYSTEMS OF THE ZIEGLER-NATTA TYPE AND METHOD FOR PRODUCTION THEREOF | Basell Polyolefine GmbH (DE) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002032969-A2 | CATALYTIC SYSTEMS OF THE ZIEGLER-NATTA TYPE AND METHOD FOR PRODUCTION THEREOF | BASELL POLYOLEFINE GMBH (DE) | 2002-04-25 | — | — | WO | disclosed |
| US-6228792-B1 | CATALYST INCLUDING CERTAIN ALKYL SUBSTITUTED PYRIDINES AS ELECTRON DONORS TO IMPROVE MELT FLOW RATIO AND ORGANOMAGNESIUM COMPOUND TO IMPROVE CATALYST ACTIVITY | W. R. GRACE & CO.-CONN. | 2001-05-08 | — | — | US | disclosed |
| EP-1058696-A1 | DONOR-MODIFIED OLEFIN POLYMERIZATION CATALYSTS | W.R. Grace & Co.-Conn. (US) | 2000-12-13 | — | — | EP | disclosed |
| WO-1999043722-A1 | DONOR-MODIFIED OLEFIN POLYMERIZATION CATALYSTS | W.R. GRACE & CO.-CONN. (US) | 1999-09-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030220498-A1 | Iron catalyzed cross coupling reactions of aromatic compounds | ARRB1, RBX1, CYP4X1 | KCNH2 1010/4885GPR84 547/4885CYP19A1 301/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.