Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CXCR3 | P49682 | 3/20 | 0.36 |
| ▸ | ACLY | P53396 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 3/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.34 |
| ▸ | PDE4A | P27815 | 2/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.34 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.34 |
| ▸ | CTSD | P07339 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PFKFB4 | Q16877 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1157767 | 0.85 | PDE4A (0.40) | TAS2R14PDE4BALDH1A1CXCR3XDH | |
| SCHEMBL1157932 | 0.76 | PDE4B (0.36) | PDE4BALDH1A1PTGDR2PDE4APDE4C | |
| SCHEMBL4206163 | 0.76 | PDE4A (0.38) | PDE4BALDH1A1PDE4APDE4CPDE4D | |
| SCHEMBL6071029 | 0.75 | PDE4A (0.43) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL1157355 | 0.74 | PDE4A (0.51) | TAS2R14PDE4BALDH1A1XDHPTGDR2 | |
| SCHEMBL2931327 | 0.73 | PDE4B (0.41) | PDE4BALDH1A1XDHPTGDR2PDE4A | |
| SCHEMBL1156850 | 0.70 | PDE4A (0.46) | PDE4BALDH1A1PDE4APDE4CPDE4D | |
| SCHEMBL4198462 | 0.70 | PDE4B (0.54) | PDE4BALDH1A1PDE4APDE4CPDE4D | |
| SCHEMBL1157495 | 0.69 | PDE4A (0.47) | PDE4BALDH1A1PDE4APDE4CPDE4D | |
| SCHEMBL1157468 | 0.69 | PDE4A (0.51) | PDE4BALDH1A1PTGDR2PDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060211865-A1 | Use of pyridine N-oxide analogs at doses which do not induce emesis | SCHUMACHER RICHARD A | 2006-09-21 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060211865-A1 | Use of pyridine N-oxide analogs at doses which do not induce emesis | PDE4A, PDE4B, PDE3B | TAS2R14 850/4885PDE4B 2/4885ALDH1A1 1154/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.