Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8344612 | 1.00 | GSK3B (0.73) | GSK3BGSK3A | |
| SCHEMBL8345510 | 0.88 | GSK3B (0.75) | GSK3BGSK3A | |
| SCHEMBL6071677 | 0.88 | GSK3B (0.75) | GSK3BGSK3A | |
| SCHEMBL8343916 | 0.85 | GSK3B (0.83) | GSK3BGSK3A | |
| SCHEMBL8344625 | 0.84 | GSK3B (1.00) | GSK3BGSK3A | |
| SCHEMBL6071428 | 0.82 | GSK3B (0.76) | GSK3BGSK3A | |
| SCHEMBL6071408 | 0.82 | GSK3B (0.76) | GSK3BGSK3A | |
| SCHEMBL6071672 | 0.81 | GSK3B (0.76) | GSK3BGSK3A | |
| SCHEMBL6071679 | 0.81 | GSK3B (0.76) | GSK3BGSK3A | |
| SCHEMBL6071214 | 0.81 | GSK3B (0.76) | GSK3BGSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060167020-A1 | Pyrazolopyrimidines as kinase inhibitors | SMITHKLINE BEECHAM CORPORATION | 2006-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060167020-A1 | Pyrazolopyrimidines as kinase inhibitors | MAP3K12, MAP3K5, MAP3K2 | GSK3B 591/4885GSK3A 662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.