Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 17/20 | 0.53 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10447781 | 0.79 | NOTUM (0.78) | NOTUMKEAP1CYP19A1 | |
| SCHEMBL4808980 | 0.77 | NOTUM (0.63) | NOTUMKEAP1CYP19A1 | |
| SCHEMBL1188176 | 0.76 | NOTUM (0.52) | NOTUMKEAP1CYP19A1 | |
| SCHEMBL4803886 | 0.75 | NOTUM (0.53) | NOTUMKEAP1CYP19A1 | |
| Hydrochloric Acid SCHEMBL9293653 | 0.74 | NOTUM (0.51) | NOTUMKEAP1 | |
| SCHEMBL75570 | 0.73 | NOTUM (0.63) | NOTUMKEAP1CYP19A1 | |
| SCHEMBL29701202 | 0.72 | NOTUM (0.52) | NOTUM | |
| SCHEMBL1163413 | 0.72 | NOTUM (0.61) | NOTUMKEAP1CYP19A1 | |
| SCHEMBL20409464 | 0.72 | NOTUM (0.61) | NOTUMKEAP1CYP19A1 | |
| SCHEMBL29800355 | 0.71 | NOTUM (0.53) | NOTUMKEAP1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060160794-A1 | Tachykinin receptor antagonists | ELI LILLY AND COMPANY | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160794-A1 | Tachykinin receptor antagonists | TACR1, TACR2, PROKR1 | NOTUM 4194/4885KEAP1 1536/4885CYP19A1 2652/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.