Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.74 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.55 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.44 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | RORB | Q92753 | 1/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29410732 | 0.86 | TSHR (1.00) | TSHRMAPK1PTGS1CES2MAPT | |
| SCHEMBL39591 | 0.86 | TSHR (1.00) | TSHRMAPK1PTGS1CES2MAPT | |
| Fluoroacetate SCHEMBL28251890 | 0.86 | TSHR (0.69) | TSHRMAPK1PTGS1CES2SRD5A2 | |
| Thioglycolic Acid SCHEMBL9661898 | 0.84 | TSHR (0.67) | TSHRMAPK1PTGS1CES2SRD5A2 | |
| Benzoic Acid SCHEMBL28155298 | 0.84 | TSHR (0.67) | TSHRMAPK1PTGS1CES2SRD5A2 | |
| Hydrochloric Acid SCHEMBL4372377 | 0.84 | TSHR (0.95) | TSHRMAPK1PTGS1CES2MAPT | |
| Iodide SCHEMBL31305312 | 0.84 | TSHR (0.95) | TSHRMAPK1PTGS1CES2MAPT | |
| Hydrochloric Acid SCHEMBL2790297 | 0.84 | TSHR (0.95) | TSHRMAPK1PTGS1CES2MAPT | |
| Hydrochloric Acid SCHEMBL30953679 | 0.84 | TSHR (0.95) | TSHRMAPK1PTGS1CES2MAPT | |
| Water SCHEMBL7109306 | 0.84 | TSHR (0.95) | TSHRMAPK1PTGS1CES2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060241149-A1 | Chemical compounds | ADAMS JERRY L | 2006-10-26 | — | — | US | disclosed |
| EP-1581514-A2 | CHEMICAL COMPOUNDS | SmithKline Beecham Corporation (US) | 2005-10-05 | — | — | EP | disclosed |
| WO-2004043379-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060241149-A1 | Chemical compounds | CHKB, MAP3K20, MAP3K6 | TSHR 3952/4885MAPK1 459/4885PTGS1 1192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.