Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE1A | P54750 | 1/20 | 0.33 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.33 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6072461 | 0.91 | FFAR4 (0.34) | PDE1APDE1BPDE1CFFAR4EZH2 | |
| Hydrochloric Acid SCHEMBL6072214 | 0.90 | TDP1 (0.32) | TDP1IRAK4FFAR4EZH2MAPT | |
| SCHEMBL6071808 | 0.90 | GAA (0.33) | TDP1IRAK4FFAR4EZH2MAPT | |
| SCHEMBL6072481 | 0.90 | IDO1 (0.33) | TDP1IRAK4FFAR4MAPT | |
| SCHEMBL6072106 | 0.90 | IDO1 (0.33) | TDP1IRAK4FFAR4S1PR1MAPT | |
| SCHEMBL6071599 | 0.89 | TDP1 (0.32) | TDP1IRAK4FFAR4 | |
| Hydrochloric Acid SCHEMBL6071761 | 0.89 | GAA (0.33) | TDP1IRAK4FFAR4MAPT | |
| Hydrochloric Acid SCHEMBL6072515 | 0.89 | TDP1 (0.32) | TDP1IRAK4FFAR4 | |
| SCHEMBL6072201 | 0.88 | TDP1 (0.39) | TDP1IRAK4MAPT | |
| SCHEMBL6072104 | 0.87 | FFAR4 (0.33) | TDP1IRAK4FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060106048-A1 | Furoisoquinoline derivative and use thereof | PASCALI, PETROS P. (CY) | 2006-05-18 | — | — | US | disclosed |
| EP-1541576-A1 | FUROISOQUINOLINE DERIVATIVE AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2005-06-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060106048-A1 | Furoisoquinoline derivative and use thereof | PDE3B, PDE2A, PDE3A | PDE1A 168/4885PDE1B 100/4885PDE1C 189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.