Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 7/20 | 0.58 |
| ▸ | TPMT | P51580 | 1/20 | 0.48 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | ATIC | P31939 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.38 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30211325 | 1.00 | TP53 (0.58) | TP53TPMTAKR1C4AKR1C3AKR1C2 | |
| SCHEMBL23803710 | 0.98 | TP53 (0.56) | TP53TPMTAKR1C4AKR1C3AKR1C2 | |
| SCHEMBL31491424 | 0.86 | TP53 (0.58) | TP53TPMTAKR1C4AKR1C3AKR1C2 | |
| SCHEMBL10942697 | 0.82 | TP53 (0.53) | TP53TPMTAKR1C4AKR1C3AKR1C2 | |
| SCHEMBL3371190 | 0.81 | TPMT (0.52) | TP53TPMTTTRHPGDHSD17B10 | |
| SCHEMBL25756313 | 0.81 | TP53 (0.49) | TP53TPMTAKR1C4AKR1C3AKR1C2 | |
| SCHEMBL29661971 | 0.81 | TP53 (0.53) | TP53TPMTAKR1C4AKR1C3AKR1C2 | |
| SCHEMBL867685 | 0.81 | TP53 (0.53) | TP53TPMTAKR1C4AKR1C3AKR1C2 | |
| SCHEMBL19730670 | 0.79 | TP53 (0.50) | TP53TPMTAKR1C4AKR1C3AKR1C2 | |
| SCHEMBL25756297 | 0.78 | HMGB1 (0.48) | TP53AKR1C4AKR1C3AKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230190792-A1 | TOPICAL PREPARATIONS | Epitheal Limited (IE) | 2023-06-22 | — | — | US | disclosed |
| US-20230190792-A1 | TOPICAL PREPARATIONS | Epitheal Limited (IE) | 2023-06-22 | — | — | US | disclosed |
| US-20230190792-A1 | TOPICAL PREPARATIONS | Epitheal Limited (IE) | 2023-06-22 | — | — | US | disclosed |
| US-9005873-B2 | Composition for forming resist underlayer film for EUV lithography | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2015-04-14 | — | — | US | disclosed |
| US-20140099791-A1 | COMPOSITION FOR FORMING RESIST UNDERLAYER FILM FOR EUV LITHOGRAPHY | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2014-04-10 | — | — | US | disclosed |
| US-20120040291-A1 | COMPOSITION FOR FORMING RESIST UNDERLAYER FILM FOR EUV LITHOGRAPHY | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2012-02-16 | — | — | US | disclosed |
| US-5094943-A | Superoxide dimutase | BOEHRINGER MANNHEIM GMBH (DE) | 1992-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230190792-A1 | TOPICAL PREPARATIONS | SLC39A11, SLC30A5, SLC30A7 | TP53 308/4885TPMT 506/4885AKR1C4 907/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.