Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | NPY1R | P25929 | 17/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6072779 | 0.86 | NPY1R (0.41) | HRH1KCNH2CYP2D6CHRM1NPY1R | |
| SCHEMBL6072962 | 0.85 | NPY1R (0.42) | HRH1KCNH2CYP2D6CHRM1NPY1R | |
| SCHEMBL6072930 | 0.83 | NPY1R (0.42) | HRH1KCNH2CYP2D6CHRM1NPY1R | |
| SCHEMBL6072854 | 0.83 | NPY1R (0.39) | HRH1KCNH2CYP2D6CHRM1NPY1R | |
| SCHEMBL6072689 | 0.80 | NPY1R (0.39) | HRH1KCNH2CYP2D6CHRM1NPY1R | |
| SCHEMBL6073225 | 0.80 | NPY1R (0.41) | HRH1KCNH2CYP2D6CHRM1NPY1R | |
| SCHEMBL4850333 | 0.78 | HRH1 (0.63) | HRH1KCNH2CYP2D6CHRM1 | |
| SCHEMBL6073300 | 0.78 | NPY1R (0.40) | HRH1KCNH2CYP2D6CHRM1NPY1R | |
| SCHEMBL6072807 | 0.76 | HRH1 (0.60) | HRH1KCNH2CYP2D6CHRM1 | |
| SCHEMBL4843808 | 0.74 | HRH1 (0.64) | HRH1KCNH2CYP2D6CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006019497-A2 | SLEEP-INDUCING COMPOUNDS AND METHODS RELATED THERETO | NEUROCRINE BIOSCIENCES, INC. (US) | 2006-02-23 | — | — | WO | disclosed |