Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 18/20 | 0.56 |
| ▸ | PPARA | Q07869 | 11/20 | 0.55 |
| ▸ | PPARD | Q03181 | 5/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6073212 | 0.97 | PPARA (0.57) | PPARGPPARAPPARDCYP2C9KCNH2 | |
| SCHEMBL6073122 | 0.94 | PPARG (0.58) | PPARGPPARAPPARDCYP2C9KCNH2 | |
| SCHEMBL6073186 | 0.94 | PPARG (0.58) | PPARGPPARACYP2C9KCNH2 | |
| SCHEMBL6073052 | 0.94 | PPARG (0.55) | PPARGPPARAPPARDCYP2C9KCNH2 | |
| SCHEMBL6073226 | 0.92 | PPARG (0.54) | PPARGPPARAPPARD | |
| SCHEMBL6073064 | 0.92 | PPARG (0.62) | PPARGPPARA | |
| SCHEMBL6073250 | 0.91 | PPARA (0.53) | PPARGPPARAPPARDCYP2C9KCNH2 | |
| SCHEMBL6073153 | 0.91 | PPARA (0.53) | PPARGPPARAPPARDCYP2C9KCNH2 | |
| SCHEMBL6073171 | 0.90 | PPARG (0.58) | PPARGPPARA | |
| SCHEMBL6073248 | 0.89 | PPARA (0.56) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006117743-A1 | SUBSTITUTED AROMATIC COMPOUNDS AS ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | disclosed |