Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8616070 | 0.83 | BRD4 (0.54) | BRD4HSD17B10POLBALDH1A1HPGD | |
| SCHEMBL8616068 | 0.78 | BRD4 (0.55) | BRD4HSD17B10POLBALDH1A1HPGD | |
| SCHEMBL10822262 | 0.77 | BRD4 (0.62) | BRD4HSD17B10POLBALDH1A1HPGD | |
| SCHEMBL30892502 | 0.77 | BRD4 (0.62) | BRD4HSD17B10POLBALDH1A1HPGD | |
| SCHEMBL171580 | 0.75 | KMT2A (0.70) | BRD4POLBALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL30356246 | 0.75 | KMT2A (0.70) | BRD4POLBALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL9287644 | 0.75 | HSD17B10 (0.68) | BRD4HSD17B10POLBALDH1A1HPGD | |
| SCHEMBL11786081 | 0.74 | KMT2A (0.55) | BRD4HSD17B10POLBALDH1A1HPGD | |
| SCHEMBL8886874 | 0.74 | HSD17B10 (0.66) | BRD4HSD17B10POLBALDH1A1HPGD | |
| SCHEMBL2538370 | 0.74 | BRD4 (0.58) | BRD4HSD17B10POLBALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006102069-A2 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF HYPERTENSION AND GASTROINTESTINAL DISORDERS | MICROBIA, INC. (US) | 2006-09-28 | — | — | WO | disclosed |