Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 13/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 13/20 | 0.48 |
| ▸ | PDE4A | P27815 | 11/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 11/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 2/20 | 0.44 |
| ▸ | ACACA | Q13085 | 2/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6640329 | 0.82 | CACNA1H (0.52) | MAPK14ACACBACACA | |
| SCHEMBL6640331 | 0.82 | CACNA1H (0.52) | MAPK14ACACBACACA | |
| SCHEMBL6637597 | 0.80 | KDM4E (0.58) | MAPK14ACACBACACA | |
| SCHEMBL6637593 | 0.80 | KDM4E (0.58) | MAPK14ACACBACACA | |
| SCHEMBL6642459 | 0.80 | KDM4E (0.58) | MAPK14ACACBACACA | |
| SCHEMBL6640560 | 0.79 | TDP1 (0.58) | MAPK14ACACBACACA | |
| SCHEMBL6640567 | 0.79 | TDP1 (0.58) | MAPK14ACACBACACA | |
| SCHEMBL6638918 | 0.78 | ACACB (0.55) | MAPK14ACACBACACA | |
| SCHEMBL6638926 | 0.78 | ACACB (0.55) | MAPK14ACACBACACA | |
| SCHEMBL6458829 | 0.77 | ACACB (0.47) | MAPK14ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006011035-A1 | NOVEL DIPEPTIDYL PEPTIDASE IV INHIBITORS; PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LTD. (US) | 2006-02-02 | — | — | WO | disclosed |