Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 13/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4850682 | 0.86 | HRH1 (0.61) | HRH1CYP2D6CHRM1HTR2AKCNH2 | |
| SCHEMBL4842386 | 0.71 | HRH1 (0.76) | HRH1CYP2D6CHRM1HTR2AKCNH2 | |
| SCHEMBL4851107 | 0.65 | HRH1 (0.66) | HRH1CYP2D6CHRM1HTR2AKCNH2 | |
| SCHEMBL4847813 | 0.64 | HRH1 (1.00) | HRH1CYP2D6CHRM1HTR2AKCNH2 | |
| SCHEMBL4850242 | 0.63 | HRH1 (0.79) | HRH1CYP2D6CHRM1HTR2AKCNH2 | |
| SCHEMBL6073265 | 0.62 | HRH1 (0.61) | HRH1CYP2D6CHRM1HTR2AKCNH2 | |
| SCHEMBL4850470 | 0.62 | HRH1 (0.67) | HRH1CYP2D6CHRM1HTR2AKCNH2 | |
| SCHEMBL6072764 | 0.62 | HRH1 (0.65) | HRH1CYP2D6CHRM1HTR2AKCNH2 | |
| SCHEMBL6072589 | 0.62 | HRH1 (0.59) | HRH1CYP2D6CHRM1HTR2AKCNH2 | |
| SCHEMBL4850999 | 0.61 | HRH1 (0.60) | HRH1CYP2D6CHRM1HTR2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006019497-A2 | SLEEP-INDUCING COMPOUNDS AND METHODS RELATED THERETO | NEUROCRINE BIOSCIENCES, INC. (US) | 2006-02-23 | — | — | WO | claimed |