Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 10/20 | 0.50 |
| ▸ | PPARA | Q07869 | 7/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | TACR2 | P21452 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5422785 | 0.92 | PPARG (0.59) | PPARGPPARAKMT2ATSHRMEN1 | |
| SCHEMBL6073017 | 0.90 | PPARG (0.54) | PPARGPPARAKMT2ATSHRMEN1 | |
| SCHEMBL6073101 | 0.88 | PPARG (0.53) | PPARGPPARAKMT2ATSHRMEN1 | |
| SCHEMBL6073021 | 0.87 | PPARG (0.54) | PPARGPPARAKMT2ATSHRMEN1 | |
| SCHEMBL6073107 | 0.84 | KMT2A (0.50) | PPARGPPARAKMT2ATSHRMEN1 | |
| SCHEMBL6073000 | 0.84 | PPARG (0.49) | PPARGPPARAKMT2ATSHRMEN1 | |
| SCHEMBL6073003 | 0.84 | PPARG (0.50) | PPARGPPARAKMT2ATSHRMEN1 | |
| SCHEMBL6073180 | 0.84 | KMT2A (0.56) | PPARGPPARAKMT2ATSHRMEN1 | |
| SCHEMBL6513163 | 0.82 | PPARA (0.58) | PPARGPPARATSHRBLMMAPT | |
| SCHEMBL6073197 | 0.81 | KMT2A (0.54) | PPARGPPARAKMT2ATSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006117743-A1 | SUBSTITUTED AROMATIC COMPOUNDS AS ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | disclosed |