Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 8/20 | 0.72 |
| ▸ | GAA | P10253 | 7/20 | 0.72 |
| ▸ | RAB9A | P51151 | 1/20 | 0.72 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.58 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.56 |
| ▸ | ERN1 | O75460 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | THRB | P10828 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.53 |
| ▸ | MPI | P34949 | 3/20 | 0.53 |
| ▸ | RECQL | P46063 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17927362 | 1.00 | POLB (0.72) | POLBGAARAB9AALOX12NOX4 | |
| SCHEMBL6073641 | 1.00 | POLB (0.72) | POLBGAARAB9AALOX12NOX4 | |
| SCHEMBL15951402 | 0.84 | POLB (1.00) | POLBGAARAB9AALOX12NOX4 | |
| SCHEMBL135614 | 0.81 | CA12 (0.61) | POLBGAARAB9AKDM4EMAPT | |
| SCHEMBL133729 | 0.81 | CA12 (0.61) | POLBGAARAB9AKDM4EMAPT | |
| SCHEMBL30251630 | 0.81 | CA12 (0.61) | POLBGAARAB9AKDM4EMAPT | |
| SCHEMBL133728 | 0.81 | CA12 (0.61) | POLBGAARAB9AKDM4EMAPT | |
| SCHEMBL2316674 | 0.80 | POLB (0.69) | POLBGAARAB9AALOX12NOX4 | |
| SCHEMBL11420096 | 0.79 | CA12 (0.59) | POLBGAARAB9AKDM4EMAPT | |
| SCHEMBL11420073 | 0.79 | CA12 (0.59) | POLBGAARAB9AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277554-B1 | PROCESS FOR THE PREPARATION OF HYDROXYBENZALDOXIME-0-ETHERS | BAYER AG (DE) | 1991-04-17 | — | — | EP | claimed |
| EP-0229641-B1 | PROCESS FOR THE PREPARATION OF HYDROXYBENZALDOXIME O-ETHERS | BAYER AG (DE) | 1990-10-03 | — | — | EP | claimed |
| WO-2006135763-A2 | INHIBITORS OF DNA REPAIR ENZYMES AND METHODS OF USE THEREOF | THE JOHNS HOPKINS UNIVERSITY (US) | 2006-12-21 | — | — | WO | disclosed |
| EP-0229641-B1 | PROCESS FOR THE PREPARATION OF HYDROXYBENZALDOXIME O-ETHERS | BAYER AG (DE) | 1990-10-03 | — | — | EP | disclosed |
| EP-0360255-A2 | Photosensitive relief printing plate and photosensitive intaglio printing plate | TORAY INDUSTRIES, INC. (JP) | 1990-03-28 | — | — | EP | disclosed |
| EP-0218123-B1 | PROCESS FOR THE PREPARATION OF HYDROXY-BENZALDOXIME-O-ETHERS | BAYER AG (DE) | 1989-03-22 | — | — | EP | disclosed |
| EP-0230230-A3 | PROCESS FOR THE PREPARATION OF HYDROXYBENZALDOXIME O-ETHERS | BAYER AG (DE) | 1988-06-15 | — | — | EP | disclosed |
| EP-0230230-A2 | Process for the preparation of hydroxybenzaldoxime O-ethers | BAYER AG (DE) | 1987-07-29 | — | — | EP | disclosed |
| EP-0229641-A2 | Process for the preparation of hydroxybenzaldoxime O-ethers | BAYER AG (DE) | 1987-07-22 | — | — | EP | disclosed |
| EP-0218123-A1 | Process for the preparation of hydroxy-benzaldoxime-O-ethers | BAYER AG (DE) | 1987-04-15 | — | — | EP | disclosed |