SCHEMBL6073846

SCHEMBL6073846

CCOC(=O)CN(Cc1cccc(OCCN(C)c2nc3ccccc3o2)c1)C(=O)Oc1cccc(C)c1

nearest known ligand 0.51

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARG P37231 18/20 0.51
PPARA Q07869 11/20 0.48
PPARD Q03181 8/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6073113 0.95 PPARG (0.53) PPARGPPARAPPARD
SCHEMBL6073250 0.92 PPARA (0.53) PPARGPPARAPPARD
SCHEMBL6073617 0.91 PPARG (0.51) PPARGPPARAPPARD
SCHEMBL6073176 0.91 PPARG (0.52) PPARGPPARAPPARD
SCHEMBL6073201 0.90 PPARG (0.53) PPARGPPARAPPARD
SCHEMBL6073417 0.88 PPARG (0.57) PPARGPPARAPPARD
SCHEMBL6073164 0.88 PPARG (0.51) PPARGPPARAPPARD
SCHEMBL6073286 0.86 PPARG (0.58) PPARGPPARA
SCHEMBL6073212 0.86 PPARA (0.57) PPARGPPARAPPARD
SCHEMBL6073122 0.85 PPARG (0.58) PPARGPPARAPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006117743-A1 SUBSTITUTED AROMATIC COMPOUNDS AS ANTIDIABETIC AGENTS RANBAXY LABORATORIES LIMITED (IN) 2006-11-09 WO disclosed