Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 20/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6074229 | 1.00 | TACR1 (0.62) | TACR1CYP2D6KCNH2 | |
| SCHEMBL6228274 | 0.96 | TACR1 (0.62) | TACR1CYP2D6 | |
| SCHEMBL6228277 | 0.96 | TACR1 (0.62) | TACR1CYP2D6 | |
| SCHEMBL6233827 | 0.92 | TACR1 (0.61) | TACR1CYP2D6 | |
| Hydrochloric Acid SCHEMBL7599484 | 0.91 | TACR1 (0.60) | TACR1CYP2D6 | |
| Hydrochloric Acid SCHEMBL6227539 | 0.91 | TACR1 (0.60) | TACR1CYP2D6 | |
| SCHEMBL6452148 | 0.91 | TACR1 (0.58) | TACR1CYP2D6 | |
| SCHEMBL6073720 | 0.89 | TACR1 (0.61) | TACR1CYP2D6 | |
| SCHEMBL6073522 | 0.89 | TACR1 (0.61) | TACR1CYP2D6 | |
| SCHEMBL7118326 | 0.89 | TACR1 (0.61) | TACR1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7119207-B2 | Benzoamide piperidine containing compounds and related compounds | PFIZER INC (US) | 2006-10-10 | — | — | US | disclosed |