Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 20/20 | 0.67 |
| ▸ | ADRB2 | P07550 | 14/20 | 0.67 |
| ▸ | ADRB1 | P08588 | 12/20 | 0.67 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.55 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.55 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.55 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6074305 | 1.00 | ADRB3 (0.67) | ADRB3ADRB2ADRB1ADRA2AADRA2B | |
| SCHEMBL6074876 | 0.92 | ADRB3 (0.56) | ADRB3ADRB2ADRB1 | |
| SCHEMBL6074885 | 0.92 | ADRB3 (0.56) | ADRB3ADRB2ADRB1 | |
| SCHEMBL6075138 | 0.89 | ADRB3 (0.70) | ADRB3ADRB2ADRB1ADRA2AADRA2B | |
| SCHEMBL6075126 | 0.89 | ADRB3 (0.70) | ADRB3ADRB2ADRB1ADRA2AADRA2B | |
| SCHEMBL6075428 | 0.88 | ADRB3 (0.86) | ADRB3ADRB2ADRB1ADRA2AADRA2B | |
| SCHEMBL6075435 | 0.88 | ADRB3 (0.86) | ADRB3ADRB2ADRB1ADRA2AADRA2B | |
| SCHEMBL6074736 | 0.87 | ADRB3 (0.70) | ADRB3ADRB2ADRB1ADRA2AADRA2B | |
| SCHEMBL6074373 | 0.87 | ADRB3 (0.75) | ADRB3ADRB2ADRB1ADRA2AADRA2B | |
| SCHEMBL6074382 | 0.87 | ADRB3 (0.75) | ADRB3ADRB2ADRB1ADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7022716-B2 | Cyclic amine phenyl beta-3 adrenergic receptor agonists | WYETH (US) | 2006-04-04 | — | — | US | disclosed |