Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 19/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 10/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 9/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6073869 | 0.89 | ADRB3 (0.59) | ADRB3ADRB1ADRB2 | |
| SCHEMBL6073975 | 0.87 | ADRB3 (0.67) | ADRB3ADRB1ADRB2 | |
| SCHEMBL6074507 | 0.86 | ADRB3 (0.64) | ADRB3ADRB1ADRB2 | |
| SCHEMBL6073971 | 0.86 | ADRB3 (0.51) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7246049 | 0.85 | ADRB3 (0.54) | ADRB3ADRB1ADRB2 | |
| SCHEMBL6801052 | 0.84 | ADRB3 (0.59) | ADRB3ADRB1ADRB2 | |
| SCHEMBL6074614 | 0.83 | ADRB3 (0.60) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7640888 | 0.83 | ADRB3 (0.60) | ADRB3ADRB1ADRB2 | |
| SCHEMBL6800700 | 0.82 | ADRB3 (0.67) | ADRB3ADRB1ADRB2 | |
| SCHEMBL6073810 | 0.82 | ADRB3 (0.59) | ADRB3ADRB1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7022716-B2 | Cyclic amine phenyl beta-3 adrenergic receptor agonists | WYETH (US) | 2006-04-04 | — | — | US | disclosed |